HSA approves updated Covid-19 vaccine by Moderna to target Omicron sub-variants

The updated Spikevax vaccine can be used by those aged six months and above. PHOTO: ST FILE

SINGAPORE – The Health Sciences Authority (HSA) has approved Moderna’s updated vaccine against Covid-19 to protect against current Omicron sub-variants of the virus.

HSA said on Friday that it reviewed data showing the updated vaccine could boost immune response to the main Omicron variants that are spreading, including XBB.1.5, EG.5 (Eris) and the emerging BA.2.86. 

The updated Spikevax vaccine can be used by those aged six months and above.

The Ministry of Health said on Friday it expects the updated vaccine by Moderna to arrive in Singapore by end-November. It added that the Expert Committee on Covid-19 Vaccination is currently reviewing data of the updated vaccine and will make its recommendations on who should receive it.

This comes as Singapore goes through another Covid-19 wave, with estimated daily cases rising from about 1,000 four weeks ago to more than 2,000 in the past three weeks.

The updated Spikevax vaccine works in the same way as the original one, and includes a monovalent component that corresponds to the Omicron XBB.1.5 variant. It has the same quality, safety and efficacy, and HSA expects the updated vaccine “to retain the favourable benefit-risk balance” of the original vaccine. 

This is the second updated Covid-19 vaccine authorised by HSA after Pfizer’s updated Comirnaty vaccine was approved on Sept 12. Stock is expected to arrive from end-October.

HSA said regular updating of approved Covid-19 vaccines is necessary to ensure their continued effectiveness, similar to the approach for seasonal influenza vaccines, which are updated every six months.

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