CORVIA MEDICAL RELEASES TWO-YEAR CLINICAL TRIAL RESULTS CONFIRMING SUSTAINED BENEFIT AND SAFETY OF ITS ATRIAL SHUNT IN HEART FAILURE PATIENTS

Key Facts

Corvia Medical, Inc, a company dedicated to transforming the treatment of heart failure, today announced two-year results from its REDUCE LAP-HF II randomized clinical trial confirming safety and sustained efficacy of the Corvia® Atrial Shunt in properly selected heart failure patients with preserved (HFpEF) or mildly reduced (HFmrEF) ejection fraction.
Corvia InterAtrial Shunt Device (IASD) "The two-year REDUCE LAP-HF II findings demonstrate the longer-term safety of the Corvia Atrial Shunt and support what we observed at one year, that in properly selected patients, atrial shunting appears to have lasting clinical benefit in the reduction of heart failure events," said Finn Gustafsson, MD, Professor of Cardiology, University of Copenhagen.
REDUCE LAP-HF II is the world's first phase III trial to evaluate safety and efficacy of an atrial shunt in heart failure patients.
Patients with the Corvia Atrial Shunt, which is implanted between the left and right atria, showed a significant 50% reduction in the rate of HF events and a sustained improvement in quality of life compared to sham control, with 42% greater improvement in Kansas City Cardiomyopathy Questionnaire (KCCQ) overall summary score.